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Toxicology

Michał Książkiewicz
Forensic expert in toxicology and physical chemistry
Senior research and development specialist

Toxicological Laboratory

Expert Analysis for Forensics and Forensic Toxicology

The Toxicological Laboratory operating within Masdiag Laboratory specializes in toxicological and forensic analyses for judicial purposes. We conduct research on biological materials such as blood, urine, and vitreous humor.
We perform:
  • quantitative determination of 34 most commonly detected substances affecting the central nervous system (CNS), including in drivers (APPENDIX 2),
  • confirmatory testing for presence of approximately 300 substances, including drugs, new psychoactive substances (so-called designer drugs) and medications (APPENDIX 1),
  • analysis of 4-hydroxybutyric acid (GHB) content, known as the "date rape drug",
  • quantitative determination of ethyl alcohol consumption marker (phosphatidylethanol – PEth) allowing determination of frequency and quantity of consumed ethyl alcohol (degree of addiction)
  • quantitative determination of ethyl and methyl alcohol and identification of other non-consumable alcohols (blood and urine).

There is also the possibility of performing qualitative and/or quantitative determinations of substances outside the above lists, using methods compliant with the Regulations of the Minister of Health of the Republic of Poland* i.e., LC-MS/MS after prior cost estimation and feasibility assessment for such analysis.

*REGULATION OF THE MINISTER OF HEALTH dated July 16, 2014, regarding the list of substances acting similarly to alcohol and the conditions and method of conducting tests for their presence in the body
REGULATION OF THE MINISTER OF HEALTH dated February 16, 2023, regarding testing for the presence of alcohol or substances acting similarly to alcohol in the employee's body

Our laboratory guarantees the highest quality of analyses, compliant with ISO 15189 standard, using modern research methods based on liquid chromatography and mass spectrometry and meeting rigorous standards, continuously validated through participation in proficiency testing (LGC Standards in the QUARTZ program).
Standard turnaround time for most methods does not exceed 10 working days from the day the sample is received at the laboratory. We perform toxicological analyses in urgent modes depending on the Client's needs within 48 hours or even 24 hours from sample receipt at the laboratory. Results are sent to the Client electronically or physically in their chosen format.
In case of court proceedings, there is the possibility of analyzing other substances, both qualitatively and quantitatively, outside the standard lists. We also offer court expert reports based on our research results for judicial and administrative proceedings.

Services for Individual Clients, Scientific Units and State Institutions

Beyond forensic/toxicological activities, Masdiag Laboratory also provides analytical services for individual clients, scientific centers and state institutions, including:
  • Quantitative determination of 34 most commonly detected CNS-affecting substances in drivers and employees – research conducted on blood and urine samples in cooperation with transport companies, fire departments, police, border guards, penitentiary units and addiction therapy centers, etc.
  • Quantitative determination of active pharmaceutical substances and their metabolites – analysis performed in various biological materials (blood, urine, serum, saliva, plasma, tissue lyophilizates) for pharmacodynamic and pharmacokinetic purposes.

Jarosław Bukowski
CEO of Masdiag DNA
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The interest in the broad field of criminology has resulted in the creation of a subsidiary company, Masdiag DNA - Forensic Expertise Center (www.masdiagdna.pl). The company offers services in: biological testing (DNA analysis, paternity determination), dactyloscopy, traceology, mechanoscopy, weapons and ammunition analysis, retrospective accounting, document and handwriting examination, forensic medicine, anthropology, phonoscopy and many others.