Quantitative determination of 3-O-methyldopa in DBS by LC-MS/MS technique
- Test objective: The 3-O-methyldopa determination is used as a screening test for L-amino acid decarboxylasedeficiency (AADC deficiency, ORPHA:35708).
- Method of testing: High-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS
- Analysed substances: 3-O-methyldopa (3-OMD)
- Type of test material: Dry blood spot
- Test category: DBS, Metabolomics